x inactivation造句

• The Xist promoter of XIC is the master regulator of X inactivation.
• The mechanism for X inactivation will occur during the embryonic stage.
• Skewed X inactivation has medical significance due to its impacts on X-linked diseases.
• It is unlikely for skewed X inactivation to influence recurrent miscarriages.
• X chromosomes in females undergo a process known as X inactivation.
• This cell is then able to remain pluripotent as X inactivation is not accomplished.
• A study hypothesized that skewed X inactivation may play a role in these miscarriages.
• X inactivation plays a key role in dosage compensation.
• In contrast to other MBD family members, MECP2 is X-linked and subject to X inactivation.
• There are several factors which must be taken into account when studying skewed X Inactivation.
• Xist expression and X inactivation change throughout embryonic development.
• This gene is thought to escape X inactivation.
• X inactivation is when one of the two X chromosomes in females is almost completely inactivated.
• OK cells were originally cultured as a source of X chromosomes for studies on X inactivation.
• XIC regulates Xist in cis X inactivation, where Tsix, an antisense of Xist, downregulates the expression of Xist.
• Skewed X inactivation has been correlated with several autoimmune diseases, including Autoimmune Thyroid Disease ( ATD ) and Scleroderma.
• Mammalian X-chromosome inactivation is initiated from the X inactivation centre or " Xic ", usually found near the centromere.
• Could this " skewed X inactivation, " which otherwise didn't harm the women, be a significant cause of recurrent miscarriages?
• The gene also consists of an Xist Inactivation Center ( XIC ), which plays a major role in X inactivation.
• This gene was also the first example of a gene subject to X inactivation in human while escaping it in mouse.